The highly potent botulinum neurotoxin serotype A (BoNT/A) inhibits neurotransmitter release at neuromuscular junctions resulting in flaccid muscle paralysis, respiratory arrest and death.In order to reach their neuronal cell targets, BoNT/A must cross epithelial cell barriers lining the intestines and airways.The toxin is produced as a large prote
The messages which can be discerned in the sculpture programme of the Arch of Constantine are here discussed, taking as a point of departure the collective memories of late-antique Rome.The direct involvement of Constantine in the erection of the Arch is sustained through a comparison with other examples of Constantinian public art, architecture, a
Background: Pyometra is a disease characterized by the collection of pus in the uterus.The clinical characteristics and etiology of pyometra have not been sufficiently described.In this study, we investigated the clinical characteristics, epidemiology, outcomes, and risk factors of septic shock in patients with pyometra.Methods: Patients with pyome
Purpose: Emergency physicians are witnesses to the impact of socioeconomic determinants of health on physical and psychiatric illness.Understanding structural barriers to the right to health (RTH) serves as a foundation for interventions to promote health equity.This study was performed to determine self-described barriers to fulfillment of the RTH